Cycloartane type triterpenoid isolated from the leaves of Brucea Javanica (l.) Merr

Abstract

Phytochemical investigation on the leaves of Brucea javanica (L.) Merr had been carried out. The powdered dried leaves were extracted with methanol using Soxhlet extraction method to get methanol crude extract. The methanol crude extract had been partitioned to get nhexane, chloroform and ethyl acetate crude extracts. The n-hexane crude extract was fractionated and purified to afford 9,19-cyclolanost-24-
en-3-acetate (1). The structure of this compound was elucidated on the basis of spectroscopic data and also comparison with data reported in the literature. Antioxidant test was carried out on the n-hexane crude extract and the pure compound using DPPH method. The result showed that both crude extract and pure compound were inactive as antioxidant agents.